|
|
Build Your Online Product Catalogs?
| Product Name: |
Esculentoside A
|
| Supply Ability: |
|
| Related proudcts |
|
| Specifications |
50-98% |
| Price Term: |
|
| Port of loading: |
|
| Minimum Order |
|
| Unit Price: |
|
|
Esculentoside A Inhibits Tumor Necrosis Factor, Interleukin-1, and Interleukin-6 Production Induced by Lipopolysaccharide in Mice
To investigate the influence of esculentoside A (EsA) on immunological function and its mechanism of antiinflammation. METHODS: Interleukin-1 production was measured by thymocyte co-stimulating assay; the radioactivity of [^3H]arachidonic acid (AA) was used to evaluate the release of AA; prostaglandin E2 production was measured with radioimmunoassay (RIA); IL-2 and IFN-¦Ã were ***ected by ELISA method. RESULTS: EsA (3-12¦Ìmol/L)could potently inhibit the production of IL-1 and PGE2 from both silent and LPS induced macrophages.EsA had no significant effect on the release of AA from murine macrophages. EsA could inhibit the production of IL-2 from murine lymphocytes induced by ConA, but not affect the production from silent lymphocytes. EsA showed no effect on the production of IFN-¦Ã from both silent and ConA induced lymphocytes. CONCLUSION:EsA could affect the immunological function through inhibiting the production of IL-2 from activated splenocytes and the inhibition of production of IL- 1 and PGE2 might be one of the anti-inflammation mechanisms of EsA.
|
| Company: |
Shaanxi Supplier Biological Technology Co., Ltd.
|
| Contact: |
Ms. zhang lily |
| Address: |
dianzi sanlu |
| Postcode: |
710065 |
| Tel: |
86 29 82139722 |
| Fax: |
86 29 81873931 |
| E-mail: |
|
|
|
|
Home
